Multiply from left to right (although you don't have to do this I just personally find it easier)
(-2 * -3)(-1)(-4)
(6)(-1)(-4)
^^^A negative times a negative is a positive
(6* -1)(-4)
(-6)(-4)
^^^Positive times a negative is a negative
(-6 * -4)
(24)
-2(-3)(-1)(-4) = 24
Hope this helped!
~Just a girl in love with Shawn Mendes
